What is Nexium?

Nexium is an orally administered pill/ tablet used to treat symptoms of acid reflux, ulcers, and certain esophageal issues. It belongs to the category of Proton Pump Inhibitors (PPIs) and contains the compound Esomeprazole Magnesium. An Over-The-Counter drug, Nexium does not require a prescription and is available at all pharmacies. All the chemical compositions present in Nexium are available on the package instructions and should be confirmed once before use even if you have used the drug before.

Nexium is available in reputed online pharmacies and is available through online prescription for people wishing to avail the benefits of home delivery of medication or for those who are too sick or ill to travel to the nearest pharmacy. Ensure that you read all the instruction information, chemical compositions, and ingredients available in Nexium before you take delivery of the medicine.

Nexium is available under different brand names (with a slight change in chemical composition) like Omeprazole, Losec, Prilosec, Prilosec OTC, Zegerid, Zegerid OTC, Lansoprazole, and Pantoprazole.


What is Nexium used for?

Nexium, like all other Proton Pump Inhibitors (PPIs), works in treating symptoms of acid reflux, stomach ulcers, Gastroesophageal Reflux Disease (GERD), and conditions like overproduction of stomach acid in Zollinger-Ellison syndrome. Nexium is also used to treat and reduce the risk of stomach ulcers due to excessive consumption of medicines like ibuprofen, ketorolac, and naproxen.

Nexium is helpful in treating symptoms of Nonerosive Reflux Disease (NERD; regurgitation and heartburn that is unrelated to tissue damage), duodenal ulcers (caused by the Helicobacter pylori bacteria), and reflux esophagitis (stomach contents being regurgitated due to tissue damage).


Who can take Nexium?

Nexium can be taken by adults and children alike. Nexium should not be used by infants under the age of 2 months, pregnant women, and breastfeeding women. Children can take Nexium if prescribed by a doctor or physician.

Adults over the ages of 50 years should consult a doctor/ physician before consuming Nexium. Nexium contains trace amounts of lactose and may be unsuitable for people who are lactose intolerant. Nexium capsules also contain gelatin ( a substance derived from grinding animal bones) and may be unsuitable for vegetarians and vegans.

People who have had a history with liver conditions, lupus, osteoporosis (brittle bones), osteopenia (low bone mineral density), low levels of magnesium in the blood, and allergies with esomeprazole, omeprazole, or magnesium should not take Nexium as it might have an adverse effect. People who have had hip or bone fractures should also refrain from consuming Nexium as it may increase the chance of another fracture.


Side effects of Nexium:

You should get immediate medical attention in case you have an allergic reaction to Nexium and can see a break out of hives, swelling on the face, lips, tongue, throat, and difficulty in breathing. Common symptoms of PPIs are dry mouth, sore throat, mild fever, headache, slight drowsiness, constipation, gas, stomach ache, and mild diarrhea.

In case you feel any of these, you need to get treated immediately:

  • Kidney issue – urinating excessively, bloody urine, swelling
  • Rapid increase or decrease in weight
  • Seizures (convulsions)
  • Low magnesium issues – choking feeling, fast/uneven heart rate, tremors (shaking), muscle cramps or spasms, confusion


How does Nexium work?

Nexium helps in controlling the enzymes present in the parietal cells of the stomach lining. The enzymes in the parietal cells produce hydrochloric acid that helps in the systematic breakdown of food and liquid in the stomach. Nexium helps in controlling the production of hydrochloric acid in the stomach.

If the esophageal valve (valve at the end of the esophagus – food pipe) is left open, or doesn’t shut properly, or is opened too many times, this acid, along with food particles can travel up into the esophagus. This can cause sensations of burning, heartburn, ulcers, and GERD. Nexium helps in easing the symptoms of all these conditions and controls release of acid in order to give the stomach and esophagus time to recover and heal completely.



Nexium comes in injection form (by prescription only) and in capsules/ tablets (over-the-counter and online prescriptions). Nexium tablets are a more popular choice over injections as they are cheaper and can be purchased without prescriptions. The tablets should be taken an hour before meals as they are delayed response tablets.

Based on the medical condition, Nexium is to be taken according to the instructions on the package and should be taken for the entire length of the course. Many times the symptoms are treated before the medicine can allow the stomach and esophagus to heal. Nexium tablets are to be swallowed whole with water. Do not chew or dissolve them.